CLAIReyes is an injectable under-eye skin booster built on polynucleotide (PN), salmon-derived and listed at 2 mg/ml, paired with oligopeptide-34 and sodium DNA. It is delivered by a trained professional over a short course and is reported to support skin quality around the delicate eye area, rather than acting as a filler.
What is CLAIReyes, in plain terms?
CLAIReyes is a polynucleotide booster aimed specifically at the under-eye. Its listed actives are PN at 2 mg/ml, oligopeptide-34, and sodium DNA, supplied in a 1.1 ml syringe. Polynucleotides are long-chain DNA fragments, here described as salmon-derived, purified for aesthetic use. They are studied as skin-quality and tissue-repair agents, not as volumizing fillers.
The maker positions CLAIReyes for the thin, expressive skin under the eyes, where many people want support without added bulk. Treat the ingredient list as a fact stated on the label, and the benefits below as reported claims, not guarantees for any one person.
Log Notes. This explains what CLAIReyes is and the general science, not how to use it. It gives no doses, depths, injection points, or technique, all of which live in the official guide and belong to a trained professional. Nothing here is medical advice, and this is not a do-it-yourself procedure.
What does CLAIReyes report, and what does the research say?
CLAIReyes is reported to increase collagen I expression and to support cell growth and angiogenesis (the formation of new small blood vessels). Those are the maker’s stated mechanisms for the active blend. A review of polynucleotides in aesthetic dermatology describes PN as studied for tissue regeneration and skin quality, which gives helpful context for the ingredient class.
Two honest caveats. First, much of the published evidence covers polynucleotides as a category, not this specific branded product, which is newer and less independently studied. Second, regulatory status varies by country: an under-eye booster available in one market may not be approved in another. Read reported benefits as “studied for the ingredient class,” and confirm what is authorized where you live with a provider.
What should you expect, and what’s worth tracking?
CLAIReyes is course-based; its suggested course is commonly described as around three to four sessions at two to three week intervals (the product’s own listed course, not advice). Because boosters work gradually, a single session tells you little. The change you care about shows up across the sequence and the weeks after, which is why a dated record beats memory.
A clean log for an under-eye course usually holds the date of each session, how the area felt afterward (any redness, puffiness, or tenderness, and how long it lasted), and a photo taken under consistent light with a neutral expression. That series shows direction in a way a single mirror check cannot.
This is the kind of course Dosefi is built to track: you add CLAIReyes as a treatment, log each session with its date and a before/after photo, and the interval you set surfaces the next appointment on your schedule. If you want broader context, see our primer on polynucleotides and the related under-eye booster Pure Eyes.
A grounded takeaway
CLAIReyes is a polynucleotide under-eye booster with a peptide and sodium-DNA blend, reported to support collagen and skin quality rather than to add volume. Expect gradual change across a course, keep a dated record, and leave candidacy and the procedure itself to a licensed professional. The official product guide is attached for your own reference.
Sources
- “Polynucleotides in aesthetic dermatology” review (PMC). Overview of polynucleotides as agents studied for tissue regeneration and skin quality.
